A peptide-rich moisturiser with signal peptides, amino acids, growth-factor extracts and soybean extract. Genuinely well-formulated, but the cult status outpaces the evidence. Works well; costs much more than less-famous peptide creams.
The verdict
What this is good for
✓ Great forAgingfirmnessDamaged Barrier
The formulation
Ingredient stack
Each ingredient is listed in descending concentration. Above the 1% line the order is regulated — below it, brands can list in any order.
Ingredients above the dashed gold line are dosed above 1% (the regulatory threshold) — these are what the formulation is really built on.
One of the most clinically studied peptide complexes. Works via two matrikine peptides: Palmitoyl Tripeptide-1 stimulates new collagen I, III and HA synthesis; Palmitoyl Tetrapeptide-7 reduces inflammatory cytokines that break down the dermal matrix. Together they reduce wrinkle depth and improve firmness in 4–12 weeks.
Relaxes facial muscle micro-contractions that cause dynamic wrinkles around the eyes and forehead. Often called "topical Botox" — works by interfering with the neurotransmitter release cycle at the neuromuscular junction, gently softening expression lines over 4–8 weeks of consistent use. Most effective at 5–10% concentration.
The closest active-matched alternative is the Naturium Multi-Peptide Advanced Moisturizer (66% active overlap). We found 1 option that share this product’s hero actives.
Skin Stacker is independent and receives no payment from any brand. Ingredient analysis is based on publicly disclosed INCI lists and the peer-reviewed literature. Formulations change — always re-check the label on your specific batch before using.