High-dose acetyl hexapeptide-8 — the 'topical Botox' peptide — in a minimalist water-based serum. Softens expression-line muscle activity over 4–8 weeks. Works best on forehead, crow's feet and between-brow lines.
What this is good for
✓ Great forAging
Ingredient stack
Each ingredient is listed in descending concentration. Above the 1% line the order is regulated — below it, brands can list in any order.
Ingredients above the dashed gold line are dosed above 1% (the regulatory threshold) — these are what the formulation is really built on.
position-estimated %★ brand-disclosed %1% regulatory line
What's actually doing the work
Argireline
Acetyl Hexapeptide-3 / Acetyl Hexapeptide-8
Peptide
Relaxes facial muscle micro-contractions that cause dynamic wrinkles around the eyes and forehead. Often called "topical Botox" — works by interfering with the neurotransmitter release cycle at the neuromuscular junction, gently softening expression lines over 4–8 weeks of consistent use. Most effective at 5–10% concentration.
Routine placement
Morning or evening
Similar on the shelf
Put this in context
Skin Stacker is independent and receives no payment from any brand. Ingredient analysis is based on publicly disclosed INCI lists and the peer-reviewed literature. Formulations change — always re-check the label on your specific batch before using.