Paula's Choice

Clinical 1% Retinol Treatment

SerumPremiumEvening only
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A higher-strength 1% retinol treatment buffered with peptides, vitamin C and liquorice. A serious step-up retinol for experienced users targeting wrinkles and tone; introduce slowly and pair with barrier support.

What this is good for

✓ Great forFine LinesPhotoaging PreventionRough Texture

Ingredient stack

Each ingredient is listed in descending concentration. Above the 1% line the order is regulated — below it, brands can list in any order.

Ingredients above the dashed gold line are dosed above 1% (the regulatory threshold) — these are what the formulation is really built on. Percentages are positional estimates from INCI order unless a brand discloses them.

~50–80%Aqua
~5–25%Cyclopentasilox…
~3–10%Glycerin
~2–6%Dimethicone
~1.5–4%Retinol
~1–2%3 ingredients
≤ 1% each3 more ingredients below 1%
position-estimated %1% regulatory line

What's actually doing the work

Retinol
1% Retinol
Retinoid
A vitamin A derivative converted in skin to retinoic acid. Increases cell turnover and stimulates collagen, improving fine lines, tone and texture. Introduce slowly to manage irritation; always pair with morning SPF.
Vitamin C
Tetrahexyldecyl Ascorbate
Vitamin
An antioxidant that neutralises free radicals, supports collagen synthesis and brightens uneven tone. Most photoprotective when layered under sunscreen in the morning; stability varies by form.
Peptides
Palmitoyl Peptides
Peptide
A key active in this formula. See the glossary for the full breakdown of how Peptides works, the evidence behind it, and how to use it.

Routine placement

Evening only

Looking for a dupe?

The closest active-matched alternative is the Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum (77% active overlap). We found 6 options that share this product’s hero actives.

Dupe guide
See all serum dupes for this product
Ranked by ingredient overlap, with an honest note on what’s different in each.

Similar on the shelf

Put this in context

Skin Stacker is independent and receives no payment from any brand. Ingredient analysis is based on publicly disclosed INCI lists and the peer-reviewed literature. Percentages are positional estimates from INCI order unless a brand discloses them. Formulations change — always re-check the label on your specific batch before using.