Side-by-side comparison

Paula's Choice Clinical 1% Retinol Treatment vs The Ordinary Retinol 1% in Squalane

Both serums contain Retinol, but each adds something the other doesn't. Here's where they overlap and where they split.

1Shared hero active
Paula's Choice
SerumPremiumEvening only
Fine LinesPhotoaging PreventionRough Texture

A higher-strength 1% retinol treatment buffered with peptides, vitamin C and liquorice. A serious step-up retinol for experienced users targeting wrinkles and tone; introduce slowly and pair with barrier support.

The Ordinary
SerumBudgetEvening only
AgingRough TextureDark SpotsSensitive skinDamaged barrier

The advanced-strength option in The Ordinary's retinol ladder — oil-based, no water, stable. For users who've already tolerated 0.2% and 0.5% and are ready to escalate. Expect visible purging and dryness in the first 2–4 weeks; pair with a barrier-supporting moisturiser and strict AM SPF.

The verdict

Which should you choose?

Both contain Retinol. Paula's Choice Clinical 1% Retinol Treatment adds Vitamin C and Peptides. Pick the one whose extra matches what you're treating. Paula's Choice Clinical 1% Retinol Treatment is the better fit for fine lines and preventing sun damage; The Ordinary Retinol 1% in Squalane for signs of aging and dark spots. On price, The Ordinary Retinol 1% in Squalane is the less expensive option (Budget versus Premium).

The overlap

What they share

This hero active appears in both formulas:

Retinol
The formulation

Ingredient stacks, side by side

Paula's Choice Clinical 1% Retinol Treatment — top of the list

  • Aqua~50–80%
  • Cyclopentasilox…~5–25%
  • Glycerin~3–10%
  • Dimethicone~2–6%
  • Retinol~1.5–4%

The Ordinary Retinol 1% in Squalane — top of the list

  • Squalane~50–80%
  • Caprylic/Capri…~5–25%
  • Retinol1%
  • Solanum Lycope…~2–6%
  • Simmondsia Chi…~1.5–4%
  • Rosa Rubiginos…~1–2%

● marks ingredients that appear near the top of both lists. Percentages are positional estimates from INCI order, not disclosed doses.

At a glance

The specs

Paula's Choice Clinical 1% Retinol TreatmentThe Ordinary Retinol 1% in Squalane
CategorySerumSerum
Price tierPremiumBudget
Best forFine Lines, Photoaging Prevention, Rough TextureAging, Rough Texture, Dark Spots
Usage notesEvening onlyEvening only
Shared hero activesRetinol
Questions

Common questions

Is the Paula's Choice Clinical 1% Retinol Treatment or The Ordinary Retinol 1% in Squalane better?
It depends on what you're treating. Both contain Retinol; Paula's Choice Clinical 1% Retinol Treatment adds Vitamin C and Peptides.
What's the difference between the Paula's Choice Clinical 1% Retinol Treatment and The Ordinary Retinol 1% in Squalane?
Paula's Choice Clinical 1% Retinol Treatment's hero actives are Retinol, Vitamin C and Peptides. The Ordinary Retinol 1% in Squalane's are Retinol. They also sit in different price tiers (Premium versus Budget).
Are the Paula's Choice Clinical 1% Retinol Treatment and The Ordinary Retinol 1% in Squalane dupes for each other?
Partly. They share Retinol, but Paula's Choice Clinical 1% Retinol Treatment's Vitamin C and Peptides aren't in the other, so they aren't full substitutes.
Can I use the Paula's Choice Clinical 1% Retinol Treatment and The Ordinary Retinol 1% in Squalane together?
There's no benefit to using two retinoids at once, and it raises the risk of irritation. Pick one.
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