Retinoic Acid / Prescription Vitamin A / Retin-A
The active form of Vitamin A — the most potent and clinically studied retinoid. Binds directly to RAR receptors at full strength. FDA-approved for acne and photodamage. The initial retinoid reaction is more intense than retinol but subsides in 4–12 weeks. Prescription only in most countries.
Prescription only. PM, pea-sized amount for entire face. Begin at 0.025% and titrate under dermatologist guidance. Strict daily SPF mandatory. Contraindicated in pregnancy.
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