Acetyl Octapeptide-3
An extended version of Argireline with two additional amino acids, designed to interact with SNAP-25 protein more efficiently. Inhibits SNARE complex formation to relax muscles driving expression wrinkles. Manufacturer data claim greater potency than Argireline; no independent head-to-head trial has been published.
At these concentrations this ingredient should appear above the 1% line on the INCI list. If you see it listed after preservatives or fragrance allergens, the dose is likely too low to work as marketed.
Topical serum 4–8%, AM and/or PM. Most potent applied to expression-prone areas before lighter serums set.
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