Side-by-side comparison

Anua Heartleaf Quercetinol Pore-Deep Cleansing Serum vs Naturium Niacinamide Serum 12%

Both serums contain Niacinamide, but each adds something the other doesn't. Here's where they overlap and where they split.

2Shared hero actives

Anua

Heartleaf Quercetinol Pore-Deep Cleansing Serum

SerumBudgetMorning or evening

OilinessAcneRedness

A heartleaf-heavy serum with niacinamide, zinc PCA and fermented extracts. Positioned for oily, congested or early-acne skin — anti-inflammatory and mildly sebum-regulating without a classic BHA.

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Naturium

Niacinamide Serum 12%

SerumBudgetMorning or evening

Dark SpotsOilinessAcneRough Texture

Higher-dose niacinamide than the classic 10% formulations, with zinc PCA, centella and ginger. At 12% there's modestly better pore and sebum performance, though some very sensitive skin can flush — patch test first.

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The verdict

Which should you choose?

Both contain Niacinamide. Anua Heartleaf Quercetinol Pore-Deep Cleansing Serum adds Zinc. Pick the one whose extra matches what you're treating. Anua Heartleaf Quercetinol Pore-Deep Cleansing Serum is the better fit for redness; Naturium Niacinamide Serum 12% for dark spots and rough texture. Both sit in the Budget price tier.

The overlap

What they share

These hero actives appear in both formulas:

NiacinamideCentella Asiatica

The formulation

Ingredient stacks, side by side

Anua Heartleaf Quercetinol Pore-Deep Cleansing Serum — top of the list

Houttuynia Cor…~50–80%
Water~5–25%
Niacinamide~3–10%
1,2-Hexanediol~2–6%
Butylene Glycol~1.5–4%
Glycerin~1–2%
Propanediol~1–2%
Zinc PCA~1–2%
Panthenol~1–2%
Hamamelis Virg…~1–2%

Naturium Niacinamide Serum 12% — top of the list

Water~50–80%
Niacinamide12%
Glycerin~3–10%
Butylene Glycol~2–6%
Propanediol~1.5–4%
Zinc PCA~1–2%
Centella Asiat…~1–2%

● marks ingredients that appear near the top of both lists. Percentages are positional estimates from INCI order, not disclosed doses.

At a glance

The specs

	Anua Heartleaf Quercetinol Pore-Deep Cleansing Serum	Naturium Niacinamide Serum 12%
Category	Serum	Serum
Price tier	Budget	Budget
Best for	Oiliness, Acne, Redness	Dark Spots, Oiliness, Acne
Usage notes	Morning or evening	Morning or evening
Shared hero actives	Niacinamide and Centella Asiatica

Questions

Common questions

Is the Anua Heartleaf Quercetinol Pore-Deep Cleansing Serum or the Naturium Niacinamide Serum 12% better?

It depends on what you're treating. Both contain Niacinamide; Anua Heartleaf Quercetinol Pore-Deep Cleansing Serum adds Zinc.

What's the difference between the Anua Heartleaf Quercetinol Pore-Deep Cleansing Serum and the Naturium Niacinamide Serum 12%?

Anua Heartleaf Quercetinol Pore-Deep Cleansing Serum's hero actives are Niacinamide, Centella Asiatica and Zinc. Naturium Niacinamide Serum 12%'s are Niacinamide and Centella Asiatica.

Are the Anua Heartleaf Quercetinol Pore-Deep Cleansing Serum and Naturium Niacinamide Serum 12% dupes for each other?

Partly. They share Niacinamide, but Anua Heartleaf Quercetinol Pore-Deep Cleansing Serum's Zinc isn't in the other, so they aren't full substitutes.

Can I use the Anua Heartleaf Quercetinol Pore-Deep Cleansing Serum and Naturium Niacinamide Serum 12% together?

Usually, yes. Apply the thinner texture first, then the thicker one, and patch-test when introducing anything new.

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